The results of a new study published in the journal "Science" underscore the importance of the role of tumor neoantigens in the response of cancer patients to immunotherapy, the most promising treatment for cancer. The neoantigens, called 'seeds' are biological markers that are only found in cancer cells, and according to the authors of this work there are some types of cancer that contain in themselves this seeds for their own destruction, something that would allow specific treatments according to the immune systems of patients.  

In recent years, immunotherapies, such as blocking immunological checkpoints or check-points, have shown promising results in the clinic. However, the biggest problem is that only about 20% of patients respond to these therapies. This has led many research groups to work on understanding the factors that determine the successful response.